Julia Bailey-Serres
Professor of Genetics

Plant Biochemistry and Molecular Biology Ph.D., University of Edinburgh, Scotland 1986 NIH Postdoctoral Fellows (1986 - 1989) USDA Individual Postdoctoral Fellow (1989 - 1990), University of California, Berkeley VOICE: 951-827-3738 EMAIL: julia.bailey@ucr.edu

My group studies signal transduction mechanisms and gene regulation in plants in response to environmental stress and during development. Our primary interest is the response of plants to oxygen deprivation, brought about by flooding or high metabolic activity. We study the initiation and modulation of signal transduction inr response to oxygen deprivation that leads to differential transcription and translation. Current research projects include dissection of ROP GTPase and MAPK mediated signal transduction, elucidation of proteins of unknown function that are critical to stress responses and development of techniques for evaluation of cell-specific mRNAs and cellular sub-populations of mRNAs (i.e. polyribosomal mRNAs). We use Arabidopsis and rice as model systems. Our studies incorporate molecular and cellular biology, genetics and biochemistry, high-throughput gene expression analyses, bioinformatics and proteomics.

RECENT PUBLICATIONS

Baxter-Burrell, A., Yang, Z., Springer, P.S. and Bailey-Serres, J. (2002) RopGAP4-dependent Rop GTPase rheostat control of Arabidopsis oxygen deprivation tolerance. Science 296(5575):2026-2028.

Kawaguchi R. and Bailey-Serres, J. (2002) Regulation of translational initiation in plants. Current Opinion in Plant Biology. 5:460-465.

Kawaguchi , R., Williams, A.J., Bray E.A. and Bailey-Serres, J. (2003) Water-deficit-induced translational control in Nicotiana tabacum Plant Cell and the Environment. 26:221-229.

Williams, A.J., Werner-Fraczek, J., Chang I.-F. and Bailey-Serres, J. (2003) Regulated phosphorylation of 40S ribosomal protein S6 in root tips of maize. Plant Physiology. 132:2086-2097.

Kawaguchi , R., Girke, T. Bray E.A. and Bailey-Serres, J. (2004) Differential mRNA translation contributes to gene regulation under non-stress and dehydration stress conditions in Arabidopsis thaliana . Plant Journal. 38:823-839.

Fukao, T. and Bailey-Serres, J. (2004) Hypoxia responses in plants – A balancing act? Trends in Plant Sciences. 9(9):449-456.

Chang, I.F., Szick-Miranda, K., Pan S. and Bailey-Serres, J. (2005) Proteomic characterization of evolutionarily conserved and variable proteins of Arabidopsis thaliana cytosolic ribosomes. Plant Physiology. 137(3):848-862.

Kawaguchi , R. and Bailey-Serres, J. (2005) mRNA sequence features responsible for translational regulation in Arabidopsis. Nucleic Acids Research 33(3):955-965.

Horan, K., Lauricha, J., Bailey-Serres, J., Raikhel, N. and Girke, T. (2005) Genome Cluster Database: A sequence family analysis platform for Arabidopsis and Oryza sativa. Plant Physiology. 138: 47-54.

Zanetti, M.E., Chang I.-.F, Galbraith D.W., Bailey-Serres, J. (2005) Immuno-affinity purification of polyribosomal complexes of Arabidopsis for global analysis of gene expression. Plant Physiology. 138:624-635.

PROJECT WEBSITES

http://bioinfo.ucr.edu/projects/internal/Unknowns/external/index.html

http://bioweb.ucr.edu/databaseWeb/index.jsp